A 38-year review of oral schwannomas and neurofibromas in a Brazilian population: clinical, histopathological and immunohistochemical study
Abstract The benign peripheral nerve sheath tumours are rare lesions mainly represented by schwannoma and neurofibroma. The present
work evaluated the clinical and histopathological features of schwannomas and neurofibromas of the oral cavity diagnosed in
a Brazilian population. Among 9.000 cases of oral lesions archived from 1970 to 2008, four schwannomas and 12 neurofibromas
were identified, microscopically revised and immunohistochemically certified through a panel including monoclonal antibodies
(anti-S100, vimentin, HHF-35 and desmin). From biopsy and histological sections records, clinical and histopathological data
were retrieved, reviewed and statistically analysed. Predominantly, schwannomas affected non-white males (3:1), with an age
and size averages of 34.7&nbs...
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